uman Menopausal Gonadotropins (hMG)

Human menopausal gonadotropin (hMG) is normally taken to help induce ovulation for the purposes of IVF and IUI. They contain both luteinizing hormone (LH) and follicle stimulating hormone (FSH), which are needed for ovulation to occur. hMG is extracted from the urine of postmenopausal women and purified before it is used.

How hMG Works and Who Benefits

Human menopausal gonadotropins trigger the release of LH and FSH in the body by working on the pituitary gland. The LH and FSH released by hMG work together to cause a woman's follicles to develop and be released into her fallopian tubes. This means the egg can be fertilized. hMG is especially likely to benefit women with endometreosis, pituitary glands that do not produce LH or FSH, or ovary disorders like PCOS. hMG can also be used when Clomid appears to be ineffective.

How HMG is Taken and Its Effects and Success

Human menopausal gonadotropins are taken in the form of intramuscular injections, taken starting two or three days after menstruation begins, for seven to twelve days. A typical dosage is between 75 and 600 IU a day.

One side effect of hMG is the release of too many follicles into the ovaries (called hyperovarian stimulation). This can lead to multiple births (40% of pregnancies that start using hMG are twins or higher order multiples). You may also notice mood swings.

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